Metoclopramide is a specific blocker of dophamin and serotonin receptors. It has anti-vomiting, soothes hiccup, stimulates and regulates work of gastrointestinal tract. Tone and motor activity of the digestive organs enhance. Secretion of stomach does not change. There are notifications that this medication promotes healing of ulcers in stomach and duodenum. Metoclopramide is used as anti-vomiting drug, nausea caused by narcosis, radiotherapy, side effects of different medications (medications on basis of foxglove, cytostatic drugs: ones to suppress cell division, antibiotics etc.), diet violations, gastroesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying).

Dosage and directions

To treat GERD Metoclopramide in adults is usually taken four times a day by 10-15 mg, 30 minutes before each meal. For treatment of Gastroparesis 10 mg of Metoclopramide are administered orally four times daily, 30 minutes before each meal and at bedtime. The tabs should be swallowed without chewing with a big quantity of water.

Precautions

Avoid drinking alcoholic beverages. Do not stop taking this medication without your doctor’s permission and do not take it in qualities larger than prescribed to you. Inform your doctor about all medications and herbal products you use.

Contraindications

Hypersensitivity, when this medication is injected ability to concentrate on driving and operating machinery may decrease as Metoclopramide affects ability to high concentration of attention. Cautiousness should be experienced in patients with bleeding or blockage in the stomach or intestines, epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma), kidney or liver disease, congestive heart failure, diabetes, or a history of depression children younger than 14 y.o.

Possible side effect

Besides signs of allergy (hives, swelling of tongue, face and rash) side effects may appear as tremors, or restless muscle movements in your eyes, tongue, drowsiness, restlessness, tremor, fatigue, anxiety, insomnia, depression, seizures, fever, stiff muscles, confusion, sweating, jaundice, depression. If you experience this stop taking Metoclopramide and seek for immediate medical help.

Drug interaction

Metoclopramide is able to change absorption and effects of other drugs that are absorbed in the small intestine. It accelerates effects of alcohol, diazepam (Valium) and cyclosporine, decreases the concentrations in blood of digoxin (Lanoxin) and cimetidine (Tagamet). Metoclopramide is contraindicated to administer in patients who are treated with MAO inhibitors: isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl), and procarbazine (Matulane). Co-administration of anticholinergic drugs can decrease the effectiveness of Metoclopramide. Other medications may also interact wit Metoclopramide: bronchodilators, atropine, cyclosporine, digoxin, acetaminophen.

Missed dose

If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule.

Overdose

Symptoms of overdose may include drowsiness, confusion, tremors or uncontrolled muscle movements in face or neck, or seizure. If you think that took too much of Metoclopramide and experience symptoms listed above contact your doctor immediately, you may need a medical help.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Prevacid is used to treat and prevent such stomach diseases as ulcers, gastroesophageal reflux (GERD), Zollinger-Ellison syndrome or erosive esophagitis. It belongs to the class of proton pump inhibitors (PPIs) which application can include treatment of ulcers caused by long-term use of certain pain/anti-inflammatory drugs (NSAIDs). The mechanism of its work consists in blocking of acid production in the stomach. Its combination with antibiotics can be used to treat certain types of ulcers. This medication can be used for treatment of other conditions.

Dosage and directions

In case you taking ampicillin, cilostazol, iron, digoxin, itraconazole, sucralfate, theophylline, ketoconazole, vitamins with iron, vorconizole, or warfarin an additional monitoring of your portion or condition may be needed. Strictly follow the recommendations for using this medication provided by your health care adviser. Take this medicine in the morning on an empty stomach unless your doctor directs otherwise. Swallow the whole tablet. Do not break, crush, or chew the tablet before to swallow it. If you have trouble swallowing the capsule, you may sprinkle its contents into soft food (e.g., applesauce, yogurt or cottage cheese), or put into a small amount (2 oz or 60 ml) of juice and taken as described. Make sure that that the entire portion is taken: rinse the container with juice and drink the contents. Do not chew the food/medication mixture or prepare a supply in advance as it may aggravate side effects. Due to the interaction between Prevacid and sucralfate, as well as with the antifungals ketoconazole and itraconazole your doctor or pharmacist should choose the proper timing of each dose if it is prescribed to take Prevacid together with them. For example, if you are instructed to take sucralfate in addition to Prevacid, it is the best to take the Prevacid dose at least 30 minutes before your sucralfate. For regularity take the drug at the same time each day in order to get the most benefit from it. Do not stop taking of this medicine even if you feel palliation.

Precautions

Consult your doctor for approval before to start any or stop any medicine intake. Inform your doctor of any other medical conditions, including liver disease, other stomach problems (e.g., tumors), allergies, pregnancy, or breast-feeding which could complicate treatment. Follow all doctor’s directions using this medicine. Before taking any new medicine consult your doctor or pharmacist. Women should discuss with their doctors the benefits and risks of using this medicine during pregnancy. The medicine is unknown for its excretion with breast milk possible harm to an unborn baby. Do not breastfeed during treatment with Prevacid.

Contraindications

Prevacid is contraindicated in patients with known severe hypersensitivity to any component of the medication. It is also contraindicated in patients allergic to amoxicillin (or any penicillin), clarithromycin (or erythromycin), or any component of the formulation; concurrent use with pimozide or cisapride.

Possible side effect

Constipation or diarrhea may appear as side effects during intake of this medicine. If they persist or are bothersome, check with your doctor. Consult your doctor the soonest in case of stomach pain. An allergic reaction to this medicine is unlikely, but in some cases rash, itching, swelling, dizziness, or trouble breathing can occur. If you experience them seek immediate medical attention. If you notice the effects different from listed above inform your health care adviser or pharmacist.

Drug interaction

Some drugs may interact with this medicine resulting in undesired side effects or lost of drug efficiency as well as certain medical conditions may influence activity of Prevacid. Inform your health care adviser or pharmacist of all prescription and over-the-counter drugs that you are taking.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.

Overdose

In case of overdose, contact your local poison control center or emergency room for help without delay.

Storage

Store at room temperature between 59-86 F (15-30 C). Do not store in the room with high humidity as a bathroom.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Protonix accumulates in the tubules of parietal cells of the stomach and transforms into its active form which selectively interacts with the H+-K+-ATP-ase. Protonix inhibits this enzyme and prevents transfer of hydrogen ions from the parietal cells into the stomach cavity this way blocking the final stage of hydrochloric acid secretion. Protonix inhibits basal and stimulated (regardless type of a stimuli – acetylcholine, histamine, gastrin) secretion of hydrochloric acid. This medication is used to treat acute stage of duodenal or gastric ulcers, including those caused by treatment with anti-inflammatory non-steroid medications, gastroesophageal reflux disease (moderate and severe); Zollinger-Ellison syndrome, eradication of H. pylori in patients with a peptic ulcer to reduce the frequency of relapses.

Dosage and directions

Take exactly as administered by your doctor. Usually for patients with stomach or duodenum ulcers, gastroesophageal reflux disease Protonix is recommended as 40 mg daily dose. Treatment continues mostly during four weeks. Combined treatment with antibiotics (amoxicillin and clarithromycin) directed eradicate H. pylori in patients with ulcers in stomach and duodenum requires Protonix 40 mg daily divided in two doses: take one tablet before breakfast and before supper, do not chew or crash it, eat it whole with a glass of water. In case you purchased Protonix oral granules take them mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food for it. Do not crush, chew, or break a delayed-release tablet.

Precautions

Some conditions require longterm treatment with Protonix. This medication is known to provoke cancer in animals but it was not tested for cancer in humans. It also causes deficit of vitamin B-12. Symptoms of a vitamin B-12 shortage may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Discuss with your doctor if you are pregnant, plan to become pregnant or breastfeeding as there is no evidence on influence of this drug on an unborn baby.

Contraindications

Hypersensitivity, hepatitis and cirrhosis combined with severe liver failure.

Possible side effect

Most common side effects may appear as diarrhea, nausea, vomiting, constipation, rash and headaches, dizziness, nervousness, abnormal heartbeat, muscle pain, weakness, leg cramps and water retention. Allergic reaction is also possible: hives, swelling of face and tongue, rash.

Drug interaction

Protonix is able to decrease pH-dependent absorption of ketoconazole and other medications. Protonix also increases the absorption and concentration in blood of digoxin (Lanoxin). This may lead to reduction of ketoconazole effectiveness or increase of digoxin toxicity, respectively.

Missed dose

If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule. Never double dose this medication to compensate the missed dose.

Overdose

This medication is not expected to cause life threating side effect if it was overdosed though if you suppose that took too much of it seek for immediate medical help.

Storage

Store at room temperature between 15-30 C (59-86 F) away from light and moisture, kids and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Colospa is a musculotropic antispasmodic medication used in the treatment of irritable bowel syndrome. It is also indicated for treatment of gastrointestinal spasm caused by a primal organic disorder. Mechanism of its action consists in relaxing of gut muscles at the cellular level. Colospa blocks transfer of Na+ through fast channels of myocyte into th cell and also inhibits calcium-depot replenishment, thus it performs a dual effect on bowels causing them to relax. It does not affect muscles of bronchi or uterus. No significant inhibition of normal peristalsis has been observed. This drug is used to treat a spasm of gastrointestinal organs (including due to organic disease), intestinal colic, biliary colic, irritable bowel syndrome (symptomatic treatment of pain and cramps, and intestinal disorders and discomfort) in adults.

Dosage and directions

Recommended daily dose of Colospa is 135 mg (1 tablet) 3 times daily, preferably before meals. Gradually the dosage may be reduced when the desired effect has been obtained.

Precautions

In pregnant patients Colospa is possible to use when expected benefit of treatment exceeds potential risk for the unborn baby. Avoid driving or be specially cautious when you need to drive or operate any machinery and mechanisms due to the possible dizziness caused by Colospa. Carefulness should be exercised in patients with paralytic ileus which is obstruction caused by failure of function of the intestine. This medicine is not recommended to treat children under 10 years of age. Discuss with your doctor if you suffer from inactivity of the bowel or allergic to any sugars before to take Colospa.

Contraindications

Hypersensitivity, porphyria.

Possible side effect

Any medication may affect different people individually, symptoms of allergy (hives, rash, swelling of face) may appear. If you need more information about any other possible risks associated with Colospa, you should consult your doctor or pharmacist.

Drug interaction

This medicine is not known to interact with other medication.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.

Overdose

Overdose symptoms are unknown or may appear as over excitation of the central nervous system. Anyway if consider that you took too much of this medication consult your doctor, as you may need medical help.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Imodium is an antidiarrheal medication. It binds opioid receptors in the wall of intestine, inhibits release of acetylcholine and prostaglandins hereby reducing peristalsis, increases time needed for the food to pass through intestines. Imodium increases tone of the anal sphincter, reducing stool incontinence and urge to defecate. Imodium is used to treat diarrhea, to reduce the amount of stool in patients with ileostomy (re-routing of the bowel is brought out by a surgical opening through in the stomach).

Dosage and directions

The drug is administered for oral intake. To treat acute diarrhea in adults and elderly patients a prescribed initial dose is 4 mg, decreased to 2 mg in the future after each act of defecation in the case of loose stool. Initial dose of 2 mg is recommended for children older than 6 y.o. which maybe diminished to 2 mg after each act of defecation in the case of loose stool. Tablets of Imodium are rather fragile so do not press them through the foil. Chew the tablets before to swallow them. Do not take Imodium more than 3 times in 24 hours.

Precautions

Do not use Imodium if you are allergic to loperamide, or if you have bloody or mucous stools or ones of black and tarry color, or if you have diarrhea caused by antibiotics. Try to drink extra water and keep diet while you are taking this medication to avoid dehydration. It may take up to 48 hours of taking Imodium to improve your condition. Notify your doctor if you have lier failure, AIDS.

Contraindications

Acute dysentery and other gastrointestinal infections (caused by Salmonella, Shigella, Campylobacter), ileus , diverticulosis, acute ulcerative colitis, pseudomembranous enterocolitis (diarrhea caused by taking antibiotics), first trimester of pregnancy, lactation, infancy (younger than 6 y.o.), hypersensitivity to loperamide and/or other components of the drug.

Possible side effect

Side effects may include symptoms of allergy like hives, rash, swelling of face and tongue, dizziness, drowsiness, constipation, stomach pain or bloating, dry mouth, ongoing or worsening diarrhea, watery or bloody diarrhea, excessive gas, nausea, vomiting fever, headache, severe blistering. Stop using this medication and call your doctor at once if you experience the listed symptoms.

Drug interaction

Inform your doctor if you are takeing saquinavir (Invirase), quinidine, ritonavir. The two last medications are both P-glycoprotein inhibitors and their co-administration with Imodium may result in increase in Imodium plasma levels. Levels of saquinavir are decreased by concomitant intake of Imodium.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule. Though this medication may not need to be on a dosing schedule and take it once or twice when needed.

Overdose

Overdose symptoms are dizziness, drowsiness, unusually rare and little urination, severe stomach cramps, bloating, and vomiting. You may need immediate medical help so inform your doctor if you believe that took too much of this medication.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Zantac is a blocker of H2-histamine receptors. The mechanism of action consists in the blockade of histamine H2-receptors of parietal cells in gastric mucous layer. This medication suppresses day and night secretion of HCl (both basal and stimulated), reduces the amount of gastric juices caused by stretching of the stomach with food load and by the action of hormones and biogenic stimulants such as gastrin, histamine, acetylcholine, pentagastrin, caffeine. Zantac reduces the amount of HCl in gastric juice almost without suppressing “liver” enzymes associated with cytochrome P450. It does not affect the concentration of gastrin in plasma, production of mucus. Zantac reduces pepsin activity. This medication is use to treat and prevent stomach and duodenal ulcers, gastrointestinal disorders caused by NSAID, heartburn, hypersecretion of gastric juice, symptomatic ulcers, ulcers caused by stress, erosive esophagitis, reflux esophagitis, Zollinger-Ellison syndrome and other conditions.

Dosage and direction

Take it orally with or without food. Correction of the dose should be made in patients with significantly abnormal liver or kidney function. Besides tablets this medication maybe administered intramuscularly (IM) or intravenously.

Precautions

The Zantac effervescent tablet may contain phenylalanine. Notify your doctor if you are pregnant, plan to become pregnant or breastfeeding before to take Zantac. Risk of developing pneumonia may be increased by this medication.

Contraindications

Hypersensitivity, breastfeeding. In patients with liver of kidney failure, cirrhosis of the liver, acute porphyria (also in history), children younger than 12 y.o., pregnancy this medication should be administered with cautiousness.

Possible side effect

Besides possible allergy (hives, rash, swelling most common side effects of Zantac are constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. Rare more serious side effects are agitation, anemia, confusion, depression, easy bruising or bleeding, hallucinations, hair loss, irregular heartbeat, visual changes, jaundice.

Drug interaction

Antacids may decrease the absorption of Zantac, so their intake should be separated by 1-2 hours. Alcohol levels may increase if Zantac is taken simultaneously. This medication also increases the area under the plasma concentration time curve (AUC) and concentration of Metoprolol in blood serum, slows absorption of itraconazole and ketoconazole.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.

Overdose

If you suspect that you took too much of the medication seek for immediate medical attention. Symptoms of overdose include lack of coordination, feeling light-headed, or fainting.

Storage

Save Zantac in a dry place away from sunlight at room temperature between 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Pentasa is a medication to treat ulcerative colitis. It belogs to the group of medications called aminosalicytates. It works by inhibiting the production of inflammatory chemicals in the lining of the colon. It descreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by ulcerative colitis.

Dosage and directions

Take is exactly as directed by your doctor. Follow all recommendations. Do not crush, break, or chew a mesalamine tablet or capsule. Swallow the pill whole.Call your doctor if you find undissolved tablets in your stool.

Precautions

Discuss with your doctor if you have pyloric stenosis, allergy to sulfasalazine, congestive heart failure, liver or kidney disease.

Contraindications

Do not use the medicine if you have allergy to mesalamine or aspirin or other salicylates. Before using it discuss with you doctor if you have liver or kidney disease, pyloric stenosis, congestive heart failure, or a history of allergy to sulfasalazine.

Possible side effects

The severe side effects include: severe stomach pain, cramping, fever, headache, and bloody diarrhea. Less serious are mild nausea, vomiting, stomach cramps, diarrhea, gas; fever, sore throat, or other flu symptoms; constipation; headache or dizziness; tired feeling; or skin rash.

Drug interaction

Tell your doctor about all other medications you may use, especially azathioprine (Imuran) or mercaptopurine (Purinethol); pentamidine (Nebupent, Pentam); tacrolimus (Prograf); amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet); antibiotics (capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled); antiviral medicines such as acyclovir (Zovirax), adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid); or aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), diclofenac (Voltaren), etodolac (Lodine), indomethacin, nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.

Missed dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Overdose

Seek urgent medical help if you overdosed Pentasa. Overdose symptoms are ringing in your ears, dizziness, headache, confusion, drowsiness, sweating, shortness of breath, vomiting, and diarrhea.

Storage

Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep it out of the reach of children and away from pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Aciphex is an antiulcer medication which inhibits a proton pump (PPIs) and blocks the production of acid by the stomach. Biochemically it blocks the (H+,K+)-ATPase enzyme system hereby inhibiting the final stage of hydrochloric acid production. After peroral intake of Aciphex antisecretorial effect is reached during one hour and is maximal in 2-4 hours. This medication is used to treat ulcers in stomach, Zollinger-Ellison syndrome, gastroesophageal reflux disease, to eradicate Helicobacter pylori in patients with ulcers in stomach or chronic gastritis.

Dosage and directions

Dosage should be administered by your doctor depending on your condition. Usually in patients with an acute duodenal ulcer and c it is recommended to take 1 tab (20 mg) in morning one time a day during 4-6 weeks. When treating H. pylori infection, Aciphex may be needed for only a week. Follow all recommendations of your doctor and do not take this drug in larger amounts than it was prescribed to you. Tablets should be swallowed whole. Do not crush, split or chew them. Take Aciphex with or without meals with a big glass of water since food has little effect on its absorption.

Precautions

Notify your doctor if you have a severe liver disease, cancer of stomach before to take this drug. Use of Aciphex in children is not recommended. It is not expected to be harmful to an unborn baby, though inform your doctor if you are pregnant or breastfeeding. Some conditions are treated with a combination of Aciphex and antibiotics, so to achieve maximal effect from treatment, use all of your medications as directed by your doctor.

Contraindications

Pregnancy, breastfeeding, hypersensitivity to Aciphex or a substituted benzimidazoles: omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), and esomeprazole (Nexium).

Possible side effect

Together with symptoms of allergy (hives, rash, swelling of tongue and face) such side effects may occur: headache, dizziness, dry mouth, upset stomach or diarrhea, constipation, insomnia, nervousness, rash, or itching. Contact your doctor for help if any of the listed side effects is severe or persistent.

Drug interaction

Co-administration with the medications which absorption depends on acidity of the stomach causes interaction of medications. Aciphex and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin) causing reduction of effectiveness of the former and increase of toxicity of the latter.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.

Overdose

Symptoms of Aciphex overdose are unknown. If you consider that you took too much of the drug seek emergency medical attention.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Asacol is an anti-inflammatory drug which acts on the lining of the gut to reduce inflammation tissue damage, and diarrhea and treat ulcerative colitis, proctosigmoiditis, and proctitis. Asacol becomes active in the small intestine just before the large intestine. This drug may be also good in treatment of patients with Crohn’s disease which affects also the small bowel. Asacol contains active component mesalamine, an anti-inflammatory drug, which is released from covering only when ??>7, and olsalazine (5-aminosalicylic acid dimer) which is also active in distal segments of gastrointestinal tract.

Dosage and direction

Consult with your doctor about necessary dosage before to start treatment. Do not use in larger quantities than prescribed. Take Asacol orally with a meal or a glass of milk. Swallow the whole pill with water. Do not break, crush or chew the tablets before to swallow them. Recommended daily dose for treatment of moderately active ulcerative colitis is 4.8g divided in three intakes; treatment contiues 6 weeks in adults. Lower doses are required to treat mild acute exacerbations of ulcerative colitis in adults: daily dose of 2.4g should be taken as divided doses. Maintenance of remission of ulcerative colitis and Crohn’s ileocolitis: take up to 2.4g a day in divided doses. On impairment of renal function dosage should be adjusted. This medication is not recommended to use in children.

Precautions

Asacol is not recommended in patients with renal impairment and caution should be exercised in patients with raised blood urea or proteinuria. Use with caution in adult patients having a normal renal function. If renal failure develops in patients treated with Asacol it can be caused by mesalazine-induced nephrotoxicity. Phenergan should not be used during pregnancy, becoming pregnant or lactating without doctor’s advice. Possible adverse effects to the infant may exclude breast-feeding. Consult your doctor if you need to breastfeed your baby.

Contraindications

Asacol is not allowed to people who are hypersensitive to any of the ingredients, sensitive to salicylates, aminosalicylates or renal sensitivity to sulfasalazine. Also contraindicated in people with severe hepatic impairment, acute and chronic interstitial nephritis, gastric or duodenal ulcer, haemorrhagic tendency. Safety of the medication in pregnancy and lactation is not known.

Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include: colic, fever, nasopharyngitis, headache, severe abdominal pain, exacerbation of abdominal colitis, cramping, fever, dyspepsia, jaundice, and bloody diarrhea. Less serious include: mild nausea, vomiting, stomach cramps, diarrhea, constipation, hemorrhoids, gas, stool abnormalities, fever, sore throat, or other flu symptoms, constipation, headache or dizziness, fatigue, skin rash.

If you experience any of the symptoms while using Asacol stop taking the medication and and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Asacol should not be co-administered with medications which lower stool pH such as lactulose as they may prevent release of the active ingredient. Due to development of Reye’s syndrome Asacol and other salicylates should not be used for six weeks after receiving the chickenpox vaccine. Asacol decreases the absorption of digoxin. Asacol can potentially increase the level of thiopurine medications. If warfarin is concomitantly used with Asacol it should be monitored by healthcare provider.

Inform your doctor if you are taking the following drugs: azathioprine (Imuran) or mercaptopurine (Purinethol); pentamidine (Nebupent, Pentam); tacrolimus (Prograf); rifampin (Rifadin, Rimactane, Rifater), amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), capreomycin (Capastat), vancomycin (Vancocin, Vancoled), adefovir (Hepsera), acyclovir (Zovirax), cidofovir (Vistide), or foscarnet (Foscavir), aldesleukin (Proleukin), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), carmustine (BiCNU, Gliadel), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid); aspirin and other NSAIDs such as diclofenac (Voltaren), ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), ketorolac (Toradol), etodolac (Lodine), diflunisal (Dolobid), flurbiprofen (Ansaid), mefenamic acid (Ponstel), indomethacin (Indocin), ketoprofen (Orudis).

Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.

Overdose

Symptoms of Asacol overdose may include confusion, dehydration, diarrhea, dizziness, drowsiness, fever, headache, quick and short breathing, ringing in the ears, sweating, vomiting. If you experience one of them or any unusual symptoms call your doctor immediately.

Storage

Store at room temperature between 20-25 C (68-77 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. ??? specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Pepcid is a blocker of H2-histamine receptors. It suppresses basal production of gastric HCl as well as one stimulated by histamine, gastrin and acetylcholine. Simultaneously with decrease of HCl activity of pepsin also diminishes. Pepcid strengthens protective mechanisms of stomach mucous layer due to stimulation of mucous production rich in glycoproteins. Other H2 blockers are cimetidine (Tagamet), ranitidine (Zantac), and nizatidine (Axid). Pepcid is used to treat stomach and duodenal ulcer, hyperacidity of gastric juice, heartburn (associated with excessive acidity of gastric juice), symptomatic gastrointestinal ulcers and ones cased by stress, erosive reflux esophagitis, gastropathy caused by treatment with anti-inflammatory non-steroid medications, Zollinger-Ellison syndrome.

Dosage and directions

Recommended dose of Pepcid for treatment of duodenal ulcers is 40 mg once daily at bedtime or 20 mg twice daily. Usually it takes about 4 hours to treat ulcers. Take this medication exactly as prescribed by your physician. Do not exceed the administered amount of the medication. Chew the tablet of Pepcid before to swallow it. Shake the liquid before to eat your meal after 10-20 seconds and measure it with a special spoon.

Precautions

You should not take Pepcid if you are allergic to it and other H2 blockers. Notify your doctor if you suffer from kidney or liver disease, stomach cancer or other problems, asthma, chronic obstructive pulmonary disease, or other breathing problems, pregnant, plan to become pregnant or breastfeeding. You may need to interrupt of your treatment with Pepcid. Avoid drinking alcohol beverages.

Contraindications

Hypersensitivity, pregnancy, breastfeeding. Cautiousness should be experienced in patients with liver or kidney failure, cirrhosis, infancy.

Possible side effect

Side effects of treatment with Pepcid may include signs of allergy constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. Other major types of side effects are: agitation, anemia, confusion, depression, easy bruising or bleeding, hallucinations, hair loss, irregular heartbeat, rash, visual changes, and jaundice.

Drug interaction

Pepcid decreases metabolism of phenazone, aminophenazone, diazepam, hexobarbital, propanolol, lidocaine, phenitoin, amynophillin, theopilin, indirect anticoagulants, tricyclic antidepressants and some other medications in liver. Pepcid increases absorption of amoxicilline and clavulanic acid. Antacids and sucralfat slow its absorption. Pepcid decreases absorption of itraconazole (Sporanox) and ketokonazole (Nizoral).

Missed dose

If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule. Never double dose this medication to compensate the missed dose.

Overdose

If overdose of Pepcid was taken the following symptoms occur: nausea, vomiting, diarrhea, stomach pain, fast heart rate, or fainting. If you suppose that took too much of the drug inform your doctor about it as you may need immediate medical help.

Storage

Store at room temperature between 15 -30 C (59-86 F) away from light and moisture, kids and pets. Injection should be stored between 2-8 C (36-46 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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