Lisinopril is used to treat high blood pressure (hypertension) in adults and children 6 years and older, including renovascular, acute myocardial infarction in clinically stable condition of the patients, heart failure (adjuvant treatment), diabetic nephropathy. The principle of this drug is to relax blood vessels, causing them to expand, it can lead to prevention of occurrence of strokes, heart attacks and kidney problems. Lisinopril is also used after acute myocardial recovery, and is used with other drugs (eg, “water pills” / diuretics, digoxin) to treat heart failure. This drug belongs to a class of medications called ACE inhibitors.

Dosage and direction

Take medicine for adults 1 time per day. The dose is determined individually, depending on the evidence, the state of renal function and concomitant therapy. Typically, the initial dose is 2,5-5 mg, the average maintenance dose – 5-20 mg, the maximum daily – 80 mg.

Precautions

Treatment is carried out under regular medical supervision (water-electrolyte balance). During treatment requires monitoring of blood pressure, protein level and plasma potassium, urea nitrogen, creatinine, renal function, blood picture, body weight and dieting. You have to be careful during surgery (including dental), especially when using general anesthetics that have a hypotensive effect.

Contraindications

Hypersensitivity, pregnancy, breast-feeding.

Possible side effects

You can feel headache, dizziness, nervousness, fainting, drowsiness, insomnia, tremors, convulsions, visual disturbances, palpitations, chest pain, hypotension, arrhythmia, dry cough and malignant tumors of the lung, hemoptysis, pain when breathing, bronchitis, dry mouth, indigestion, heartburn, vomiting, diarrhea / constipation, bloating, abdominal pain, renal failure, weakening of libido, impotence, arthritis, neck pain, back pain, rash, urticaria, and syndrome of Stevens – Johnson.

Drug interactions

List of the drugs that can interact with Lisinopril: gold injections to treat arthritis, lithium (Lithobid, Eskalith), a potassium supplement such as K-Dur, Klor-Con, salt substitutes that contain potassium, insulin or diabetes medication you take by mouth, aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others, or a diuretic (water pill).

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Lisinopril overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.

Storage

Store Lisinopril at room temperature away from moisture and heat.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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This medication suppresses effects of vitamin K, which actively participates in clotting of the blood. It results in prevention of blood clot formation. Blood clots may form in different parts of body such as in vessels of extremities after periods of immobility, in vessels of lungs, around artificial heart valves causing embolism and shortness of breath, chest pain depending on the place where they block a vessel. Coumadin is used for treatment of patients with blood clots in the lower extremities, pulmonary embolism, atrial fibrillation, in certain orthopedic surgeries such as knee or hip replacements, myocardial infraction.

Dosage and direction

Never take a double dose of Coumadin. It maybe taken with or without food. Patients with liver or kidney dysfunction should take lower doses of the medication.

Precautions

Avoid eating cranberries or any cranberry herbal products, drinking alcohol and sports or activities that can result in bruising. If you need to do a lumbar puncture or any kind of surgery inform your doctor about taking Coumadin.

Contraindications

Acute bleeding, liver or kidney failure, acute arterial hypertension, pregnancy.

Possible side effect

Bleeding, necrosis of skin are among most dangerous ones. Black tarry stools, digestion disorders, nasal or gum bleeding, abundant and persisting menstrual discharge, unreasonable bruises, hair loss.

Drug interaction

Coumadin interacts with many drugs, and these interactions can be very dangerous. Mostly often such medications as aspirin, acetaminophen (Tylenol and others), alcohol, ibuprofen (Motrin), cimetidine (Tagamet), oxandrolone (Oxandrin), certain vitamins, and antibiotics should be taken into consideration while treatment with Coumadin is performed.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If it occurred do not take the missed dose and simply return to your regular schedule. Do not try to compensate a missed dose by taking an extra one. Never take a double dose of Coumadin.

Overdose

If you suspect that you took too much of the medication you may observe excessive bleeding from cuts or wounds, blood in the urine or stools, and heavy menstrual periods in women. Look for immediate medical help in such cases.

Storage

Store at room temperature in a dark dry place.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Antihypertension drug (decreasing blood pressure) belongs in a class of drugs called angiotensin converting enzyme (ACE) inhibitors. Suppressing synthesis of angiotensin II it diminishes its vasoconstrictor activity (blood vessel narrowing) and its stimulating influence on secretion (extretion) of aldosteron. The medication facilitates activity of renin in blood plasma and inhibits metabolism (destruction in organism) of badicidin. This medication also decreases total resistance of peripheral blood vessel system. Treatment with ACE inhibitors is particularly beneficial to people with congestive heart failure. The drug is also administered in hypertension, congestive heart failure, prophylactic of sudden death after myocardial infarction.

Dosage and direction

The usual dose of Altace is 2.5-20 mg a day as a single dose or two divided doses is taken in mornings with a glass of water. Patients taking diuretics or ones with renal artery stenosis may require lower doses as well as people whose age exceeds 65 y.o.

Precautions

Alcohol may lower your blood pressure and this way it increases some of the side effects of Altace. Do not use salt substitutes or potassium supplements while taking this medication. In all cases first consult your doctor before taking this drug.

Contraindications

hypersensitivity, stenosis of kidney artery, condition after kidney transplantation, aorta constriction, non-inflammatory heart diseases of uncertain or disputable origin leading to its enlargement , pregnancy, breath-feeding, severe kidney disorders, liver failure. Infants how are younger 14 y.o. For drivers and other employees who work requires high concentration of attention should be treated carefully with this medication.

Possible side effect

Kidney failure and increased levels of potassium in the blood, hypotension, collapse, heart arrhythmia are serious side effects of the Altace. Altace generally is well tolerated, and side effects are transient. Persistent dry cough, abdominal pain, constipation, diarrhea, rash, dizziness, fatigue, headache, loss of taste, loss of appetite, nausea, vomiting, fainting and numbness or tingling in the hands or feet were marked among them.

Drug interaction

The use of ACE inhibitors with potassium supplements, salt substitutes or diuretics that increase potassium in the blood are able to cause excessive potassium levels. Concomitant use of ACE inhibitors with these drugs require monitoring of potassium levels. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS) may reduce the effects of ACE inhibitors.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose

Symptoms of a Altace overdose are extreme dizziness or fainting. If you experience these symptoms call your doctor immediately.

Storage

Tablets and capsules should be stored at room temperature 15-30 C (59-86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Cartia is used in treatment hypertension, chest pain (angina) and certain heat rhythm disorders. It’s active component diltiazem belongs to the group of so called calcium channel blockers. Diltiazem works by relaxing the muscles of our blood vessel ans heart.

Dosage and directions

Take Cartia exactly as it was prescribed by your doctor. Take it with a full glass of water. Avoid crushing, chewing and breaking a tablet. Swallow it the whole.

Cartia can be only a part of a treatment program that include diet, exercise and other medications.

Precautions

This medicine can cause impairing of your thinking or reactions. Be careful driving or doing anything that requires high concentration of your reaction. Do not stop taking medication with your doctor’s agreement.

Contraindications

Do not use Cartia if you have the following conditions low blood pressure, certain heart conditions (sick sinus syndrome, AV block), if you’ve had recent heart attack. Before starting Cartia tell your doctor if you have any allergy or if you have kidney or liver disease, congestive heart failure. Tell your doctor if you are pregnant or plan to become pregnant. This medicine can cause harm to unborn baby. Diltiazem passes into breast milk. Do not use it during breastfeeding without telling your doctor.

Possible side effects

Besides allergic reactions (hives, swelling of your face, tongue, throat,difficulty breathing), you can experience such serious side effects: fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; fast or slow heartbeats, feeling light-headed, fainting, swelling, rapid weight gain, nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice. Call to you doctor if you experience one of them.

Less serious side effects:skin rash or itching, nausea, warmth, redness, tingly feeling, stuffy nose, dizziness, headache, tired feeling.

Drug interaction

Tell your doctor if you take the following medications: digoxin (digitalis, Lanoxin, Lanoxicaps), an antibiotic such as clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), or telithromycin (Ketek); an antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend); HIV/AIDS medicine ( amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir, Kaletra)); beta-blockers (atenolol (Tenormin), bisoprolol (Zebeta, Ziac), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren); amiodarone (Cordarone, Pacerone); buspirone (BuSpar); lovastatin (Mevacor); quinidine (Quinaglute, Quinidex, Quin-Release); a sedative such as midazolam (Versed) or triazolam (Halcion); cimetidine (Tagamet, Tagamet HB).

Grapefruit and grapefruit juice can interact with Diltiazem and to lead to potentially dangerous effects.

Missed dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

Symptoms of Cartia overdose are weakness, chest pain, feeling light-headed, slow heartbeat, shortness of breath, fainting. If you overdosed Cartia seek medical attention right away.

Storage

Store at room temperature away from moisture and heat.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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The medication causes antiarrhythmic and antianginal effects. Antiarrhythmic effect is stipulated by diminishing of K+ ions transportation though cell membranes of myocites and diminishing of sinus node automaticity. Cardarone automatically blocks a- and b-adrenoreceptors. Relief of paroxysmal tachycardia attacks, relief of other heart attacks and treatment of ventricular fibrillation. Cardarone is for use only in life-threatening situations and should be used strictly according to recommendations of your doctor.

Dosage and direction

Cardarone may hurt stomach so it is recommended to take it with meals and in several daily doses to minimize damage.

Precautions

Avoid drinking grapefruit juice, tanning and excessive UV irradiation, be careful doing work which requires high concentration of attention (driving and others).

Contraindications

Hypersensitivity to iodium or Cardarone. Sick sinus syndrome (sinus bradycardia, sinoatrial block) excluding cases of rythm correction with artificial pacemake. Disorders of atrioventricular or intra ventricular conduction (atrioventricular blocade of I-III degree), blocade of bundle Branch Block, disorders of thyroid gland, hypopotassiemia, pregnancy, breast-feeding, age below 18 years old, simultaneous treatment with MAO inhibitors.

Possible side effect

Lipofuscin deposit in cornea may cause appearance of shining spots or a ‘fog’ in front of eyes at bright light. Light pygmentation on open areas of skin, hypothyreosis, wheezing, cough, chest pain, trouble breathing, weight loss, thinning hair, feeling too hot or too cold, numbness, burning, pain, nausea, stomach pain. Call your doctor if you experience this or symptoms of allergy.

Drug interaction

Cardarone may interact with beta-blockers or certain calcium channel blockers leading to excessively slow heart rate or electrical impulse blockage in the heart. Blood levels of digoxin are increased at concurrent treatment with digoxin and Amiodarone. In case of treatment with digoxin its dose should be decreased by 50% when amiodarone is taken. Cardarone also increases levels of flecainide, procainamide and quinidine.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If it occurred skip the missed dose. Do not try to compensate a missed dose by taking an extra one.

Overdose

If you suspect that you took too much of the medication and experience extremely dizzy or light-headed, or fainting seek for immediate medical attention.

Storage

Keep Cordarone at room temperature, lower than 30 C (86 F).

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. ??? specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Cordarone belongs to the antiarrhythmics. It is used to correct abnormal rhythms of the heart, to treat potentially life-threatening types of abnormal heart rhythms (such as persistent ventricular fibrillation/tachycardia). It helps by making the heart beat more regularly and it works by blocking certain electrical signals in the heart that can cause an irregular heartbeat. The effects of this medication may be noted as early as three days after starting treatment, but it is usually one to three weeks before beneficial effects are seen.

Dosage and direction

You will receive your first few doses of amiodarone in a hospital setting where your heart can be monitored in case the medication causes serious side effects. The recommended adult starting dose of Cordarone is usually from 800 mg to 1,600 mg daily for the first one to three weeks in divided doses. The dose is eventually reduced to 200 mg to 400 mg daily as prescribed by your doctor and according to circumstances. Take this medication by mouth, usually once or twice daily or as directed by your doctor. Take it with or without food with a full glass of water. It is important to choose one way and take this medication the same way with every dose. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of this medication in your bloodstream. The dosage is based on your medical condition and response to treatment. Your doctor may direct you to start this medication at a higher dose and gradually decrease your dose. Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Precautions

When starting treatment with this drug, you may stay in the hospital for proper monitoring by your doctor. Cordarone may take 2 weeks or longer to have an effect in your body. This drug stays in your body for weeks to months, even after you are no longer taking it. Also serious side effects may occur weeks to months after taking Cordarone. Before taking Cordarone. Tell your doctor or pharmacist about your allergy to Cordarone, or to iodine and other allergies. Before using this medication, tell your doctor or pharmacist your medical history. You must limit alcoholic beverages.This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps by using a sunscreen and wearing protective clothing when outdoors. Before having surgery, tell your doctors or dentist about all prescription drugs, nonprescription drugs, and herbal products you use.

Contraindications

People who has very low heart rate, cardiogenic shock, second or third degree AV block (except when used with a pacemaker), hepatitis, thyroid diseas, certain lung abnormalities, an allergy to amiodarone, any ingredients of the product, or iodine should not take Cordarone. If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking amiodarone, tell your doctor about diseases you have: asthma or another lung disorder, liver disease, vision problems, high or low blood pressure, a thyroid disorder, an electrolyte imbalance (such as low levels of potassium or magnesium in your blood) or if you have a pacemaker or defibrillator implanted in your chest.

Possible side effects

Serious side effects may include lung or liver problems. Tell your doctor immediately if you notice any symptoms of lung or liver problems such as cough, shortness of breath, chest pain, coughing up blood, persistent nausea/vomiting, dark urine, severe stomach/abdominal pain, or yellowing eyes/skin.

Get emergency medical help if you have any of these signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue or throat. Less serious side effects may include feeling dizzy or tired, nausea, vomiting, stomach pain, constipation, loss of appetite, insomnia, weakness, lack of coordination or warmth, tingling, or redness under your skin.

Drug interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Cordarone may interact with drugs such as atenolol (Tenormin), propranolol (Inderal), metoprolol (Lopressor), digoxin(Lanoxin), verapamil (Calan, Isoptin, Verelan, Covera-HS) or diltiazem (Cardizem, Dilacor, Tiazac). The result of combination is an excessively slow heart rate or a block in the conduction of the electrical impulse through the heart. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose

Overdose symptoms may include weakness, slow heart rate, feeling light-headed, or fainting. Seek emergency medical attention if you think you have used too much of this medicine.

Storage

Store Cordarone at room temperature between 68-77 degrees F (20-25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Nimotop is a nimodipine. It can prevent or eliminate spasm of vessels caused by various drugs such as serotonin or histamine. Due to its the high lipophility penetrates the blood-brain barrier (BBB). Nimotop improves stability and functional capacity of neurons. The medication also affects positively learning ability and memory by blocking of Ca2+-channels in certain brain areas, such as the hippocampus and cerebral cortex.

Dosage and direction

Take the medication orally exactly as prescribed to you. Do not exceed the recommended dose. Take on an empty stomach with a full glass of water one hour before or two hours after a meal. To get the most benefit of the drug take it regularly.

Precautions

Cautiousness should be exercised in individuals with severe bradycardia, liver failure, mild or moderate hypotension, myocardial infarction associated with the failure of left ventricular, intracranial hypertension, generalized edema of the brain tissue. Avoid drinking of grapefruit juice while you ar eon Nimptop. When Nimptop is used with rifampicin effectiveness of the former can be reduced. Simultaneous adminitration of nimodipine with cimetidine or valproic acid may lead to increased concentrations of nimodipine in blood serum. Beta-blockers used together with Nimptop may cause considerable drop in blood pressure. Procainamide, quinidine used together with Nimptop may significantly increase the risk of elongation of the QT interval.

Contraindications

The medication should not be used in patients with hypersensitivity to the medication, severe hypotension, pregnant and breastfeeding women.

Possible side effect

In case of severe signs of allergy seek immediate medical care: skin rash, difficulty breathing, facial swelling, hives. Inform your doctor as soon as possible also if you experience fainting or severe dizziness, unusually fast or slow heartbeats, easy bruising or bleeding, unusual weakness, swelling in your legs or ankles.

Drug interaction

Inform your doctor about all prescribed, over-the-counter medications, herbal products and food supplements you use. Combined use of nimodipine and Fluoxetine leads to increased concentrations of nimodipine in blood serum. Prolonged use of nimodipine with Nortriptyline results in a slight increase in serum levels of nimodipine. If phenobarbital, phenytoin or carbamazepine were used for a long time before nimodipine they may reduces its bioavailability.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose.

Overdose

Symptoms of overdose which may need you to apply immediately for professional medical attention are: chest pain, dizziness, fainting, weakness, shortness of breath, an unusually fast or slow heartbeat, confusion, slurred speech, or coma.

Storage

Store in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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